Small interfering RNAs developed from double-stranded RNAs can turn on
the immune system in GM plants through the detection of virus
transcripts to degrade. Thus, the researchers designed three RNAigene
constructs based on the PVYgenome.

Using/Agrobacterium/, GM plants were generated containing the designed
constructs, and analyses showed confirmation of the transformation.
Further analysis revealed that over 67% of the GM potato plants were
resistant to PVY compared to non-GM plants, which exhibited symptoms of
viral infection. Plants generated from the three constructs showed
similar levels of resistance against PVY. No changes were observed in
the physical characteristics of the GM potato plants when compared with
the non-GM.

Comparative evaluation of resistance to potato virus Y (PVY) in three
different RNAi-based transgenic potato plants | SpringerLink
[link.springer.com]