www.checkbiotech.org ; www.raupp.info ; www.czu.cz

Why take all the trouble to dye silk when silkworms can be genetically
modified to spin any colour of the rainbow?
That?s the goal of Japanese scientists who have genetically engineered
silkworms to produce a specific colour, according to a new study.

The study?s author, Takashi Sakudoh of the University of Tokyo, said
understanding the pigment transport system of silkworms could ?pave the way
for genetic manipulation of the color and pigment content of silk.?

In nature, silkworm cocoon colours vary from white, yellow, straw, salmon,
pink and green. The colours in the silk are from natural pigments absorbed
when the silkworms eat mulberry leaves.

Japanese researchers observed in silkworms that produce white silk that the
?yellow blood,? or Y gene, was mutated. A segment of DNA had been deleted.

The Y gene enables silkworms to extract carotenoids, yellow-coloured
compounds, from mulberry leaves.

The scientists found that mutated insects produced a non-functional form of
the carotenoid-binding protein (CBP), known to aid pigment uptake.

Using genetic engineering techniques, the researchers introduced pristine Y
genes into the mutant insects.

The engineered worms produced working CBP and yellow-coloured cocoons.

The yellow colour became more vivid after rounds of crossbreeding.

Silk fibers could be produced in a flesh colour and a reddish colour, the
authors wrote in the study, published in the Proceedings of the National
Academy of Sciences of the United States.

[www.khaleejtimes.com]