Scientists Fumio Takaiwa and Lijung Yang from the National Institute of
Agrobiological Sciences (Japan) developed a universal peptide vaccine for
Japanese cedar pollinosis, a major allergy related disease in Japan. They
developed transgenic seeds containing seven new T-cell epitopes (Crp3) in
addition to the T-cell epitopes used in the 7Crp peptide. Then they
co-expressed unique T-cell epitopes (6Chao) from the Japanese cypress pollen
allergens Cha o 1 and Cha o 2 in transgenic rice seeds containing 7Crp and
Crp3. The transgenic rice seeds, containing many highly homologous T-cell
epitopes derived from cedar and cypress allergens, are expected to be
applicable to a wide range of patients suffering from these pollen
allergies.
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link.springer.com]