Genome editing has evolved from the use of chemical and physical mutagenic
agents capable of altering DNA sequences to biological tools. The advent of
these biological tools, such as ZFNs, TALENs, ODMs and CRISPR-Cas9 has
further advanced the understanding of mutagenesis such that mutations can
now be performed in a precise and directed manner resulting in gene
knock-outs and knock-ins.

These tools have rapidly incorporated themselves into agriculture and life
science biotech research resulting in new opportunities to feed the global
population. One of the best evidences of the impact of genome editing in
science is the number of publications that were published on genome editing
techniques. For example, CRISPR publications alone have increased
exponentially from 2010 to 2015. This increase proves the significance and
impact of this technology in the scientific community.

The world is currently at the crossroads of how the classic transgenic and
gene editing technologies are evaluated and how products from gene editing
should be regulated. This review from D. D. Songstad of Cibus LLC discusses
the new genome editing techniques as well as the regulatory aspects of their
products in comparison to classic transgenic crops

[www.tandfonline.com]



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