The most accurate and complete DNA analyses of the
to date has been reported in the journal Genome Research by a group of
scientists at the John Innes Centre (JIC), in collaboration with colleagues
at the Earlham Institute, The Sainsbury Laboratory, and the European
The scientists have generated a new wheat whole-genome shotgun sequence
assembly using a combination of optimized data types and an assembly
algorithm designed to deal with large and complex genomes. The new assembly
represents >78% of the genome with a scaffold N50 of 88.8 kb that has a high
fidelity to the input data.
The team identified 104,091 high-confidence protein-coding genes and 10,156
noncoding RNA genes, and confirmed three known and identified one novel
genome rearrangements. Their approach enables rapid and scalable assembly of
wheat genomes, identification of structural variants, and definition of
models, all powerful resources for trait analysis and breeding of this key
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