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New CRISPR System Enables Temporary Gene Editing
Posted by: Prof. Dr. M. Raupp (IP Logged)
Date: November 16, 2017 06:33AM

CRISPR, one of the new breeding techniques, has just gotten better. A new
enzyme called Cas13 has been developed to temporarily modify RNA. This new
CRISPR system called RNA Editing for Programmable A to I Replacement
(REPAIR) enables targeting specific RNA letters or nucleotides involved in
single-base changes. The results of the study conducted by scientists from
Broad Institute of MIT and Harvard is published in Science.

CRISPR-Cas 9 was developed to edit specific parts of the genome permanently.
With REPAIR, scientists can target single bits of messenger RNA, which can
be transient or even reversed. The edited portion may be degraded over a
period of time and the modifications made in the cell will also disappear.
Thus, REPAIR dispels safety concerns faced by the CRISPR-Cas9 system. It
also promised a broad application for research, medicine, and biotechnology.


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