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An opportunity too good to refuse
Posted by: Prof. Dr. M. Raupp (IP Logged)
Date: March 26, 2007 08:44AM

www.checkbiotech.org ; www.raupp.info ; www.czu.cz

If scientists were to discover a drug that could save children from a deadly
affliction AND help cancer patients recover from chemotherapy, they?d win
wide acclaim for making a great contribution to mankind?s well-being, March
2007 by Bill Horan.

Unfortunately, anti-biotech radicals are trying to turn a wonderful
scientific advance into a depressing political controversy. If they succeed,
an innovative new technology that could alleviate much suffering might not
reach the people who need it the most.

The drug in question already exists. In fact, it isn?t even a drug. Instead,
it?s a pair of proteins that are found naturally in mammalian breast milk,
including that of our mothers. They?re called lactiva and lysomin, and one
of their primary functions is to boost the immune systems of infants.

But some infants would benefit from a little extra. Acute infectious
diarrhea, for example, kills millions of people each year, many of them
babies. (Some researchers estimate that number is over five million children
per year) Plenty of others become very sick. Virtually all of these maladies
result from contaminated drinking water in the developing world. We can only
imagine the hopelessness felt by a mother holding her dying, dehydrated
child.

Cleaner water is the ultimate solution to this problem--but fully addressing
this root cause will take a very long time. Today, we need short-term
responses that can save lives right now. That?s why it makes sense to pursue
pharmaceutical solutions--and figure out how to deliver additional lactiva
and lysomin to at-risk children.

One of the most creative ideas involves growing these proteins in rice
plants. A biotech company is currently researching this method in Kansas .
If this project eventually succeeds, it will become much less expensive to
produce the proteins that go into the pills that can save infants from a
brutal killer.

In a recent clinical trial, 140 children with diarrhea were given an
electrolyte solution containing rice-grown lactiva and lysomin. They
recovered from their illnesses more quickly and were less likely to relapse
than children in a control group. The results were published in last month?s
Journal of Pediatric Gastroenterology and Nutrition.

Down the road, it may also be possible for rice-grown treatments to help
cancer victims recover from chemotherapy. One of the great dilemmas of
chemotherapy, of course, is that although it often represents the only hope
for cancer victims, it?s a dangerous remedy because it ravages the immune
system. Many people who have cancer don?t die from it, but from pneumonia
that they can?t fight off because of their chemo-weakened immune system.

It turns out that supplements of lactiva and lysomin may help them, too. At
the very least, a new generation of drugs derived from enhanced rice plants
could improve the survival rates of chemo patients.

So let?s recap: We have the potential to produce an inexpensive medicine
that may save the lives of infants and cancer sufferers.

This is controversial?

The enemies of biotechnology say so. They?re banking on something called the
?ick factor?--the notion that an idea is so icky that a misinformed public
will reject it. In the case of rice that produces lactiva and lysomin, the
?ick factor? depends upon disgust with the concept of putting human genes
into plants.

Sure, it sounds a little odd, especially on first glance. But rice doesn?t
produce lactiva and lysomin on its own. We essentially need to trick the
plants into making these proteins. The miracle of biotechnology is that we
can.

The opponents are waging war with propagandistic press releases. ?If these
pharmaceutical crops end up on consumers? plates, the consequences for our
health could be devastating,? claims one European protestor.

That statement is made possible by near-complete ignorance. For one thing,
the amount of protein produced in any kernel of rice is so tiny that it
would be impossible for anyone to receive a clinical dosage simply from
eating a bowl of it. For even one child to be treated, the company must have
access to a large amount of rice so they can extract and purify enough
protein for a clinical dosage.

Moreover, these crops are effectively segregated from the food chain. Kansas
isn?t a rice-producing state, which is why it?s the host of these promising
field trials.

Biotech-enhanced foods never have hurt anybody. In the not-to-distant
future, they may heal us. Genetically enhanced rice presents us with an
opportunity we?d be foolish to refuse.

[www.agweb.com]



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